PLACENTAL TRANSFER OF LIGNOCAINE FOLLOWING LUMBAR EPIDURAL ADMINISTRATION
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چکیده
منابع مشابه
Placental transfer of flunitrazepam following intramuscular administration during labour.
After a single intramuscular dose of flunitrazepam 0.015 mg kg-1 (n = 14) in women 37 to 41 weeks pregnant, the concentrations in the umbilical artery and amniotic fluid were significantly lower than in maternal venous plasma. Although the difference between the maternal venous and umbilical venous plasma concentrations was not significant, the mean fetomaternal ratio was 0.7. The plasma protei...
متن کاملThe maternal plasma levels and placental transfer of bupivacaine following epidural analgesia.
The maternal plasma levels of bupivacaine following epidural administration of 0.5 per cent solution with 1/200,000 adrenaline were determined in twelve patients in labour. After 10 ml (50 mg) peak concentrations occurred 15-30 min later and ranged from 0.22 ^ug/ml to 0.60 ,«g/ml. Plasma levels fell gradually with time after the peak until by 3 hours after injection they were all well below 0.2...
متن کاملEffect of acute hypovolaemia on lignocaine absorption and cardiovascular response following epidural block in dogs.
The effect of acute hypovolaemia (15% blood loss) on the absorption of lignocaine from the epidural space and on the cardiovascular response to epidural analgesia was studied in 10 dogs. After bleeding the net rate of systemic drug absorption was significantly reduced compared with the rate under normovolaemic conditions. Maximum blood concentrations of the drug were lower by about 30%. This fi...
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BACKGROUND Epidural steroid injections are commonly used in managing radicular pain. Most complications related to epidural injections are minor and self-limited. Flushing is considered as one such minor side effect. Flushing has been studied using various steroid preparations including methylprednisone, triamcinolone, and betamethasone but its frequency has never been studied using dexamethaso...
متن کاملA comparison of epidural anaesthesia with lignocaine, bupivacaine and a lignocaine-bupivacaine mixture in cats.
A mixture of 2% lignocaine (LIG) and 0.5% bupivacaine (BUP), at respective dose rates of 2 mg/kg and 0.5 mg/kg (LIG-BUP), was compared to LIG (4 mg/kg) and BUP (1 mg/kg) for lumbosacral epidural anaesthesia in 5 sedated cats. Each cat received all 3 treatment regimens at 1-week intervals. The cats were premedicated with an intramuscular injection of atropine sulphate (0.04 mg/kg) and ketamine h...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1968
ISSN: 0007-0912
DOI: 10.1093/bja/40.12.965